基本信息:
中文名稱 7-氯-1-環(huán)丙基-6-氟-4-氧代-1,4-二氫-喹啉-3-羧酸乙基酯
英文名稱 ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylate
英文別名 1-cyclopropyl-6-fluoro-7-chloro-4-oxo-1,4-dihydro-quinoline-3-ethyl ester;Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate;ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate;ethyl 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate;ethyl 1-cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylate;7-Chlor-1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeure-ethylester;3-Quinolinecarboxylicacid,7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-,ethyl ester;ethyl 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate;
CAS號(hào) 86483-54-7
合成路線:
1.通過(guò)2,4-二氯-5-氟苯酰氯和環(huán)丙胺合成7-氯-1-環(huán)丙基-6-氟-4-氧代-1,4-二氫-喹啉-3-羧酸乙基酯,收率約85%;
2.通過(guò)(Z)-3-環(huán)丙基氨基-2-(2,4-二氯-5-氟-苯甲?;?-丙烯酸 乙酯合成7-氯-1-環(huán)丙基-6-氟-4-氧代-1,4-二氫-喹啉-3-羧酸乙基酯,收率約92%;
中華試劑網(wǎng)提醒 合成路線僅供參考